In Parasite Eve II, at the end of the game (on any mode) the player is awarded a score based on all EXP earned in that playthrough. This score determines which rank the player is awarded, with S being the highest, then running from A down to L, being the lowest. Each rank opens up new weapons, items, and ammunition available for immediate purchase in any shops in the game during any subsequent Replay Mode.

The rank awards are cumulative, so if a player earns a B rank on one playthrough, then starts a new game using that clear save data and earns an A rank in that playthrough, then the next time Replay Mode is started using the new clear save data, both A and B rank items will be available for purchase in the shops. In this way, it is possible to earn every rank available in 13 consecutive playthroughs of the game. However, if you play through the game once more and get the same rank, you will instead be graduated to the next rank. For example, if you attain a B rank in your first playthrough, and then attain a B rank once again on a subsequent playthough with the same save file, you will then receive the A rank rewards for your next playthough.

Some modes also add a rank bonus at the end. Bounty Mode adds 1 extra rank to the player's score, Scavenger Mode adds 2 extra ranks, and Nightmare Mode adds 3 extra ranks. There are no rank bonuses for Normal or Replay Modes. These bonuses are necessary to reach ranks A and S, since it isn't possible to earn higher than rank B on a normal playthrough by earned EXP alone, unless you have at least earned a B rank once.

The item awards are ONLY available in Replay Mode. They will not be available in Bounty, Scavenger, or Nightmare modes (other than what is normally for sale).

Experience Total Rank Items
400001+ S Gunblade, Ringer's Solution, Eau de Toilette
200001-400000 A Hypervelocity, Hunter Goggles, MP Boost2
75001-200000 B MM1, Airburst, Recovery3
72001-75000 C M249, .44 MaedaSP ammo, Cola
69001-72000 D Mongoose, .44 Magnum ammo, Skull Crystal
66001-69000 E AS12, R. Slug ammo, Firefly ammo
62001-66000 F Aya Special, 9mm Spartan ammo, Ofuda
57001-62000 G Javelin, MD Player, Holy Water
51100-57000 H Pyke, Lipstick, Tactical Armor
44001-51000 I Hammer, Belt Pouch, MP Boost1
16001-44000 J M203, Protein Capsule, 9mm Hydra ammo
14501-16000 K M9, M4A1 Rifle Clip Holder, Flare
0-14500 L Monk Robe, Medicine Wheel, Recovery2
v · e · d
Aya Brea - Eve Brea - Kyle Madigan
Rupert Broderick - Eric Baldwin - Gary Douglas - Flint - Pierce Carradine - No. 9 GOLEM - Jodie Bouquet
Neo-Mitochondrial Creatures
Bass - Bat - Black Beetle - Worms (Caterpillar, Maggot) - Amoeba (Green Amoeba, Red Amoeba) - Moth - Rat - Scorpion
Artificial Neo-Mitochondrial Creatures
Stranger (Grinning Stranger, Boss Stranger, Odd Stranger, Lesser Stranger, Creeping Stranger, Horned Stranger) - Stalker (Zebra Stalker, Gray Stalker, Ivory Stalker, Skull Stalker) - Suckler (Blood Suckler, Bone Suckler, Mind Suckler, Sucklerceph) - Scavenger - Chaser (Desert Chaser, Blizzard Chaser, Mad Chaser) - Fatties (Brute, Mossback, Slouch) - Diver (Bog Diver, Sea Diver) - Stinger (Brain Stinger, Puppet Stinger) - GOLEM (Pawn GOLEM, Rook GOLEM, Knight GOLEM, Bishop GOLEM)
Watcher - Derangement Speaker
Unique Neo-Mitochondrial Creatures
Boss Stranger - No. 9 GOLEM - Gray Stalker - Burner - Blizzard Chaser - Ivory Stalker - Glutton - Generator (Proto Generator, Beta Generator) - Sea Diver - Puppet Stinger - Brahman - Eve
Abandoned Mine - Akropolis Tower - Dryfield - M.I.S.T. Headquarters - Neo Ark - Shelter
Ammunition - Armor - Bounty Points - Items - Gameplay - Modes - Rankings - Shops - Soundtrack - Weapons
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